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His current research focuses on the cell biology of cellular shape. Polarized actin filaments are common in eukaryotic cells and provide the scaffolding for cell movement and cell shape. The Guild lab uses Drosophila bristle cells as a model system to investigate actin bundle assembly and cell shape architecture by employing molecular and genetic tools to modify actin bundle assembly and confocal and electron microscopic techniques to evaluate the cell biological consequences at high temporal and spatial resolution.

Greg Guild